Added 9 October 2026 substrate /ˈsʌbˌstɹeɪt/ noun Categories: NaturePlacesEveryday Words noun ! Definition from WordNet 3.1, Princeton University. Pronunciation from Wiktionary, via Kaikki.org. More about substrate at Wordnik → Where our words come from → The substance that is acted upon by an enzyme or ferment. A surface on which an organism grows or is attached. the gardener talked about the proper substrate for acid-loving plants Any stratum or layer lying underneath another. Origin Anglicization of substratum. From Wiktionary, via Kaikki.org (CC BY-SA) Related Words: substratumaminosoilbedrockmediumbasementbottomfeedstocksupportsubstratafoundationbase Back to today's word